Effects of an in vitro vitamin D treatment on the inflammatory responses in visceral adipose tissue from Ldlr−/− mice

Atherosclerosis is associated with increased inflammation in the visceral adipose tissue (VAT). Vitamin D has been reported to modulate the inflammatory responses of stromal vascular cells (SVCs) and adipocytes in adipose tissue, but the role of vitamin D in atherosclerosis biology is unclear. This study examined the effects of in vitro 1,25-dihydroxyvitamin D3 (1,25[OH]2D3) treatment on the inflammatory […]

Transcriptome analysis of T cells from Ldlr-/- mice and effects of in vitro vitamin D treatment

Vitamin D is known for its immunosuppressive effects on T cells, suppressing Th1 and Th17 and promoting Treg differentiation. Th1 cells contribute to inflammatory responses such as inflammatory cytokine production and macrophage activation, which accelerate the progression of atherosclerosis. However, the mechanisms underlying the modulation of T cell functions by vitamin D in atherosclerosis have not been investigated. This study analyzed the gene expression profiles of T cells, using RNA-seq transcriptome analysis, to […]

Taste receptor type 1 member 3 is required for the fertility of male mice

Male infertility is a global health concern. However, its underlying pathophysiology remains unclear. Taste receptor type 1 member 3 (TAS1R3) is highly expressed in the testes, indicating its potential involvement in male fertility. Using wild-type and Tas1r3 knockout (KO) mice, we investigated whether TAS1R3 modulates male reproductive function. Tas1r3 KO mice exhibited reduced male fertility compared to WT mice, […]

Dietary Isoflavone Intake and Breast Cancer Prognosis: A Prospective Analysis and Meta-Analysis

We aimed to examine the association between dietary isoflavone intake and the risk of breast cancer recurrence and summarize evidence on the role of dietary isoflavone intake in breast cancer prognosis. This prospective study included 592 breast cancer survivors who completed a dietary assessment. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using […]

Association between Sleep Duration and Metabolic Disorders among Filipino Immigrant Women: The Filipino Women’s Diet and Health Study (FiLWHEL)

Sleep plays a complex role in metabolic regulation, and the underlying linkage has not been clearly defined. We investigated the association between sleep duration and metabolic disorders in Filipino immigrants in Korea. We analyzed 410 participants from the 2014 to 2016 baseline population of the Filipino Women's Diet and Health Study. Usual sleep duration was self-reported, […]

Development of nutrient-based nutritional standards for foodservice at shelters during disasters in the Republic of Korea

In times of disaster, simplified and minimized nutritional standards are necessary for a quick response to provide nutritious relief food. This study aimed to develop nutrient-based nutritional standards for foodservice at shelters during disasters in the Republic of Korea (South Korea). The standards were developed in 2 phases. First, nutrients to be included in the standards […]

생산자 FGI와 전문가 FGD를 통한 지역농산물을 이용한 간편식의 생산 진흥 방안 모색

This study aimed to derive measures for promoting the production of convenience foods utilizing local agricultural products. In July 2022, qualitative data were collected through focus group interviews (FGI) with six producers of convenience foods utilizing local agricultural products. Two producer FGIs were conducted online in groups of three. Problems and difficulties faced by the […]